Fig. 7

Effects of PCSK9 inhibition or statin administration on the NLRP3 inflammasome activity in respiratory epithelial cells stimulated by TGF-β1. The mRNA expression of NLRP3 (A), caspase-1 (B) and IL-1β (C) are shown. The respiratory epithelium was stimulated with 10 ng/ml of TGF-β1. Statistical analysis was performed using one-way ANOVA with Bonferroni correction. *: P < 0.05, **: P < 0.01, and ***: P < 0.001