Fig. 5

Effects of PCSK9 inhibition or statin administration on CCK expression and FFA levels in HFD mouse lungs. FFA (A–B) and CCK (C–D) protein expression in both lungs and serum were measured by ELISAs. The results are expressed as the mean ± SEM (n = 6 per group). Statistical analysis was performed using one-way ANOVA with Bonferroni correction. *: P < 0.05, **: P < 0.01, and ***: P < 0.001. FFA: free fatty acid, CCK: cholecystokinin