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Fig. 4 | Respiratory Research

Fig. 4

From: Statin administration or blocking PCSK9 alleviates airway hyperresponsiveness and lung fibrosis in high-fat diet-induced obese mice

Fig. 4

Effects of PCSK9 inhibition or statin administration on RAS activation in HFD mouse lungs. Protein expression of angiotensin II (A), angiotensin II receptor type 1 (B), and MDA levels (C) in lung homogenates and MDA (D) in serum were measured by ELISAs. The results are expressed as the mean ± SEM (n = 6 per group). Statistical analysis was performed using one-way ANOVA with Bonferroni correction. *: P < 0.05, **: P < 0.01, and ***: P < 0.001. MDA: malondialdehyde

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