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Fig. 1 | Respiratory Research

Fig. 1

From: Statin administration or blocking PCSK9 alleviates airway hyperresponsiveness and lung fibrosis in high-fat diet-induced obese mice

Fig. 1

Effects of PCSK9 inhibition or statin administration on body weight and serum biochemical marker levels in HFD-induced obese mice. (A) Experimental scheme of PCSK9 inhibition or statin treatment in HFD or normal chow-fed mice. (B) Body weight in mice on the ND or HFD. (C) Cholesterol, (D) triglyceride, (E) glucose, (F) Alanine aminotransferase (ALT), (G) Aspartate aminotransferase (AST), and (H) Alkaline phosphatase (ALP) levels were measured in serum. The results are expressed as the mean ± SEM (n = 6 per group). Statistical analysis of body weight changes was performed using repeated-measures ANOVA, and other analyses were performed with one-way ANOVA with Bonferroni correction. *: P < 0.05, **: P < 0.01, and ***: P < 0.001. ND: normal diet; HFD: high-fat diet

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Respiratory Research

ISSN: 1465-993X

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