Fig. 5
From: A novel quinoline with airway relaxant effects and anti-inflammatory properties
Expression profiling of genes related to asthma and allergy in murine lung tissue. The gene expression of pooled lung tissue mRNA from (A) PBS challenged and vehicle treated mice (Vehicle/PBS) compared with OVA challenged and vehicle treated mice (Vehicle/OVA) on day 21. Genes with a fold regulation above 2.5 is highlighted. B Mice challenged with OVA and treated with vehicle compared with mice challenged with OVA and treated with RCD405. Genes with more than a 2.5 fold increase in fold regulation in (A) are highlighted. C Mice challenged with OVA and treated with vehicle compared with mice challenged with OVA and treated with budesonide. Genes with more than a 2.5 fold increase in fold regulation in (A) are highlighted. Equal amounts of mRNA were pooled from 8 animals in each group