Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content
Fig. 3 | Respiratory Research

Fig. 3

From: Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice

Fig. 3

ISM1 deficiency exacerbates HDM-induced airway hyperresponsiveness. (A) Levels of TH2 cytokines in the BALF (n = 4–5). (B) Levels of TH1 cytokines in the BALF (n = 4–5). (C) Levels of TH17 cytokines in the BALF (n = 4–5). (D) Levels of chemokines in the lung tissue lysates (n = 4–5). Data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001, using one-way ANOVA. (E) Assessment of AHR in WT and ISM1−/− mice with or without HDM sensitization. Airway resistance was measured in response to increasing concentrations of methacholine (0, 2.5, 5, and 10 mg/mL) in PBS (n = 6). Data are presented as the mean ± SD. **P < 0.01, using two-way ANOVA. IL, interleukin; IFNγ, interferon-gamma; TNFα, tumor necrotic factor alpha; MCP-1, monocyte chemoattractant protein 1, PBS, phosphate-buffered saline

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us