Fig. 6
From: Do alternative tobacco products induce less adverse respiratory risk than cigarettes?
Chronic inhalatory exposures to EC, HTP and CC aerosols induce lung damage. Mice exposed to aerosols from alternative tobacco products and CC for 8 weeks were euthanized and BAL harvested. MPO activity, levels of NE and antioxidant potential in the BAL were measured as described previously [47] and details provided in Additional file 1. Data are presented as bar diagrams with mean ± SE. Difference between two groups is considered significant at p < 0.05 and is indicated by symbols *p < 0.05, **p < 0.01, ***p < 0.001 ****p < 0.0001, calculated after performing a non-parametric Kruskal–Wallis rank test with FDR correction for multiple comparisons by employing GraphPad Prism V.9 software (GraphPad; La Jolla, California, USA). We used n = 10 animals for air (5 M + 5F) and n = 20 animals for EC, HTP, and CC (10M + 10F) per group for each exposure condition