From: Association of advanced paternal age with lung function at school age
Crude coefficient β (95% CI)a | Adjusted coefficient β (95% CI)a | |||||
---|---|---|---|---|---|---|
30–34 years ( n = 566) | 35–39 years ( n = 398) | ≥ 40 years ( n = 159) | 30–34 years ( n = 566) | 35–39 years ( n = 398) | ≥ 40 years ( n = 159) | |
FVC (mL) | 20.51 (− 17.36, 58.37) | − 19.17 (− 59.10, 20.77) | 9.17 (− 40.16, 58.50) | 15.32 (− 12.17, 42.80) | − 16.50 (− 45.9, 12.9) | 16.49 (− 21.64, 54.62) |
FEV1 (mL) | 4.62 (− 30.02, 39.25) | − 30.02 (− 66.55, 6.51) | − 21.20 (− 66.32, 23.92) | − 1.16 (− 26.69, 24.37) | − 28.56 (− 55.87, − 1.24) * | − 20.50 (− 55.93, 14.93) |
FEV1/FVC (%) | − 1.06 (− 2.06, − 0.06) * | − 1.15 (− 2.21, − 0.09) * | − 2.29 (− 3.60, − 0.98) * | − 1.15 (− 2.20, − 0.09) * | − 1.20 (− 2.33, − 0.08) * | − 2.93 (− 4.38, − 1.47) * |
FEF75 (mL/s) | − 34.55 (− 77.52, 8.43) | − 55.56 (− 100.88, − 10.24) * | − 92.81 (− 148.80, − 36.83) * | − 34.11 (− 76.33, 8.11) | − 50.78 (− 95.95, − 5.61) * | − 99.08 (− 157.66, − 40.5) * |
PEF (mL/s) | − 43.32 (− 142.24, 55.61) | − 97.48 (− 201.80, 6.85) | − 124.87 (− 253.74, 4.01) | − 41.62 (− 132.31, 49.08) | − 88.73 (− 185.76, 8.30) | − 115.26 (− 241.11, 10.58) |
FeNO (ppb) | 1.29 (− 1.62, 4.20) | 0.78 (− 2.29, 3.84) | 0.63 (− 3.14, 4.40) | 0.38 (− 2.64, 3.40) | 0.06 (− 3.16, 3.28) | − 0.24 (− 4.40, 3.92) |