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Table 2 Association between paternal age at birth (continuous, per 5-year increase) and lung function

From: Association of advanced paternal age with lung function at school age

 

Crude coefficient β (95% CI)a

Adjusted coefficient β (95% CI)a

FVC (mL)

− 1.32 (− 13.33, 10.69)

− 0.45 (− 9.72, 8.82)

FEV1 (mL)

− 6.15 (− 17.14, 4.83)

− 5.95 (− 14.55, 2.65)

FEV1/FVC (%)

− 0.42 (− 0.74, − 0.10) *

− 0.51 (− 0.86, − 0.15) *

FEF75 (mL/s)

− 20.11 (− 33.73, − 6.49) *

− 19.86 (− 34.07, − 5.65) *

PEF (mL/s)

− 19.49 (− 50.84, 11.86)

− 16.61 (− 47.13, 13.91)

FeNO (ppb)

− 0.06 (− 0.97, 0.85)

− 0.35 (− 1.36, 0.65)

  1. CI confidence interval, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, FEF75 forced expiratory flow at 75% of FVC, PEF peak expiratory flow; ppb: parts per billion
  2. a Per 5-year increase in paternal age at birth, adjusting for age, sex, height, maternal age at birth, prematurity, birth weight, cesarean delivery, birth order, physician-diagnosed asthma, parental university education, parental allergic diseases, prenatal exposure to environmental tobacco smoke, breastfeeding, and household income
  3. * P < 0.05 is bold
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Respiratory Research

ISSN: 1465-993X

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