Fig. 3

Placebo-corrected mean change from baseline in a trough FEV1 at day 2 and b normalized FEV1 AUC0–24 (per protocol population). Data are LS means ± standard error. AUC0–24 = area under the curve from 0 to 24 h post-dose; FEV1 = forced expiratory volume in 1 s; LS = least squares. *P < .0001 vs placebo