Fig. 2

Study design. TP = treatment period. aThe figure shows an example of the washout timings for one patient. The washout period was 10 to 21 days following navafenterol or placebo, and 7 to 21 days following the active comparators indacaterol and tiotropium. Therefore the length of each washout period depended on the patient’s randomization sequence. One exception per patient of up to 28 days was considered acceptable; bdays following administration of last dose