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Figure 1 | Respiratory Research

Figure 1

From: Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2

Figure 1

Aspergillus antigen induced similar increases in BAL fluid cell counts in wild-type, Mcp-1 -/- and Ccr2 -/- mice. Total cells, macrophages, eosinophils, and lymphocytes are expressed as mean BAL fluid total cell counts ± SE from wild-type, Mcp-1 -/- and Ccr2 -/- mice (PBS-treated, N = 5 mice/group; Aspergillus antigen-treated, N = 8 mice/group; Aspergillus antigen exposure and sample collection are described in methods). Neutrophils represented <0.5% of total cells for all groups. The data shown are from one experiment and representative of three separate experiments. Asterisks (*) indicate values that are statistically significantly different (p < 0.001) compared to PBS controls.

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